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Collagen Replacement Therapy


Collagen replacement in lips and nasolabial folds

Collagen Replacement TherapyŽ is a natural, non-surgical procedure which has been used by  millions of  individuals to help reduce facial lines and wrinkles, providing immediate and visible results with minimal recovery time. In fact, many patients return to work or other activities immediately following their treatment.

The original collagen fillers, Zyderm & Zyplast Collagen, were derived from purified bovine (cow) and have been replaced by much more efficient and long lasting products.  Although still in use, these bovine products are not  used in our office and Dr. Pilest recommends the use use of fillers with no allergic potential which include  Cosmoderm or Cosmplast, Restylane Juvederm, Hylaform, Captique. or the more permanent fillers such as Radiesse (Radiance) or Sculptra.

By supplementing your skin's own collagen  we can smooth out wrinkles, most scars, replace lost facial volume, return a youthful lip border and fullness and improve the appearance of deeper frown lines.

Immediately following collagen injections normal activity can be resumed. Discomfort is minimal. The treatment sites may have a little swelling which may last a few hours and depend on the filler chosen and your skin's own individual response. There may be some slight bruising which may be covered by makeup but this is typically only with the more robust and longer lasting fillers such as Restylane, Radiesse or Sculptra.

Depending on the area, treatments usually last from three to six months or up to 5 years in the case of Radiesse.

Wrinkle Filler Product Duration

Areas most frequently treated with collagen or collagen-like fillers are :

  • Nasolabial folds (sides of the nose)
  • Perioral lines (above the lips)
  • the Vermillion ridge (top of the lip)
  • Glabellar frown lines (between the eyebrows)
  • Oral comissures (smile lines)
  • Marionette lines (lines at the ends of the mouth)
  • Crows feet
  • Acne scars and Depressed scars.


2008 © Total Dermatology is one of Southern California's top laser dermatology centers offering laser treatments for sundamage, pigmentation, acne and acne scars and Fraxel CO2 laser for 3 in 1 skin rejuvenation. A Nonsurgical Nose Job is possible with simple injections of Radiesse. Dr. Pilest, a Board Certified dermatologist and one of Orange County's most popular cosmetic dermatology specialists, offers patients in Orange County a wide variety of wrinkle fillers such as Restylane, Juvederm, Cosmoderm and Cosmoplast, Radiesse (also known as Radiance), and Sculptra. Dr. Pilest treats patients from the Newport Beach, Irvine, Laguna Beach, Laguna Hills, Tustin, Mission Viejo and Orange County area as well as cities throughout California, the United States and abroad. He is recognized as a master level injection specialist and is a national teaching faculty member for Bioform Medical. Dr. Pilest is well known for his expert treatments in managing Rosacea, acne, and hyperpigmentation.

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